The human brain holds the clues. We ask different questions.

Why do some regions of the human brain succumb to neurodegeneration while others remain resilient? We challenge conventional thinking about Alzheimer's disease and related disorders by exploring the fundamental mechanisms of brain aging, selective vulnerability, and neurodegeneration. From human brain tissue to molecular biology, genetics, biomechanics, and artificial intelligence, we bring together diverse approaches to tackle questions that no single discipline can answer. Our laboratory is a place for curious, ambitious scientists who want to push boundaries, develop bold ideas, and pursue discoveries that could reshape how we understand, diagnose, and ultimately treat diseases of the human brain.